Echinococcus granulosus is a member of the Cyclophyllidea, which comprise the majority of tapeworms that are of medical importance. The disease cystic echinococcosis, which is caused by the larval stage of E. granulosus , is considered to be one of the most dangerous worm infections in the world. Larval stages of the related tapeworms E. multilocularis and Taenia solium cause the serious and life-threatening diseases alveolar echinococcosis and neurocysticercosis, respectively. E. granulosus has a worldwide distribution.
This is a Wellcome Trust funded project to sequence the nuclear genome of E. granulosus, in collaboration with Dr. Cecilia Fernandez. The assembled sequence data suggests the genome of E. granulosus is approximately 110 MB and is being produced by illumina sequencing. We are also profiling the transcriptome of different life cycle stages of this organism using RNA-seq.
This sequencing centre plans on publishing the completed and annotated sequences in a peer-reviewed journal as soon as possible. Permission of the principal investigator should be obtained before publishing analyses of the sequence/open reading frames/genes on a chromosome or genome scale. For further information see our data release policy.
Please address all sequencing and annotation enquiries to Nancy Holroyd.