Hymenolepis microstoma is a member of the Cyclophyllidea, which comprise the majority of tapeworms that are of medical importance. Larval stages of the related tapeworms Echinococcus granulosus and Taenia solium cause the serious and life-threatening diseases cystic echinococcosis and neurocysticercosis, respectively. Hymenolepis microstoma is a rodent tapeworm, and serves as an improtant model organism for research on tapeworm physiology and development. It's entire life-cycle can be maintained in the laboratory, using rodents and flour beetles as hosts.
This is a Wellcome Trust funded project to sequence the nuclear genome of H. microstoma, in collaboration with Dr. Pete Olson, Natural History Museum, London. The assembled sequence data suggests the genome is approximately 140 MB and is being produced using 454 pyrosequencing and Illumina sequencing. We are also profiling the transcriptome of different life cycle stages of this organism using RNA-seq.
This sequencing centre plans on publishing the completed and annotated sequences in a peer-reviewed journal as soon as possible. Permission of the principal investigator should be obtained before publishing analyses of the sequence/open reading frames/genes on a chromosome or genome scale. For further information see our data release policy.
Please address all sequencing and annotation enquiries to Nancy Holroyd.
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