P. berghei is one of the four malaria species that infect murine rodents from Central Africa that are infectious to laboratory rodents and easily maintained and transmitted by Anopheles stephensi in the laboratory. It serves as a good model for the human parasites with which it shares high homology in most essential aspects of structure, biochemistry and life cycle. Genome organisation is conserved between rodent and human parasites and the two share detailed synteny.
P. berghei has an estimated genome size of 18-20 Mb, with 14 chromosomes in the size range of 0.6 Mb to 3.8 Mb. DNA for this sequencing project was obtained from asynchronous bloodstages of clone 15cy1 of the ANKA strain of P. berghei.
The genome of P. berghei ANKA has been published A comprehensive evaluation of rodent malaria parasite genomes and gene expression.
» Plasmodium berghei on GeneDB