The Plasmodium falciparum IT homepage on GeneDB

New version of the genome (August 2012)

A new assembly of the P. falciparum IT genome is now available (August 2012), replacing the version 2 sequence that has been available via PlasmoDB (since release 9.0) and the Sanger FTP site. In version 3, an additional contig has been added that contains a partial var gene (PFIT_bin11100). The new version can be viewed and searched on GeneDB. EMBL and GFF format files can be downloaded from the FTP site.

New version of the genome (November 2011)

A new assembly of the P. falciparum IT genome is now available (November 2011), replacing the version 1 sequence that has been available via PlasmoDB (since release 8.0) and the Sanger FTP site. The version 1 sequence was produced by “correcting” (or morphing) the reference 3D7 sequence, using aligned Illumina reads from IT. However, in version 2, the sequence data have been assembled de novo. A key aim for this genome project is to fully assemble the subtelomeric regions. Although we were able to correctly assemble some subtelomeric sequences onto the “core” of the genome (i.e. the interstitial or housekeeping region), many subtelomeric sequences remain problematic and are being actively refined. The annotation is automated and no manual curation has taken place.

The new version contains new systematic identifiers compliant with those now in use for 3D7. However, old identifiers remain in the database as fully searchable synonyms. The new version can be viewed and searched on GeneDB and will be loaded into PlasmoDB in early 2012. EMBL and GFF format files can be downloaded from the FTP site.

This work was funded by the Wellcome Trust [grant number WT085775/Z/08/Z] and the European Union's 7th Framework Programme (FP7/2007-2013) under grant agreement n°242095.

FTP

» Sequence data

Example Gene

» PFIT_0104800

External Database

» PlasmoDB

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» Dr. Thomas Otto