P. knowlesi is predominantly a simian-infection malaria parasite, but also causes natural infection in humans, primarily in South East Asia. P. knowlesi was the first malaria parasite in which antigen variation was demonstrated. It has close phylogenetic relationship to P. vivax, the second most important species of human malaria parasite.
We have generated a whole genome shotgun, to 8x coverage of P. knowlesi (H strain, Pk1(A+)clone). The H strain originally came from a naturally infected patient and was acquired in peninsular Malaysia in 1965. Genomic DNA was provided by Clemens Kocken (BPRC).
This genome has been published: Pain et al. (2008) The genome of the simian and human malaria parasite Plasmodium knowlesi. Nature 455:799-803.
Please address all sequencing enquiries to Dr. Ulrike Böhme.
» Plasmodium knowlesi on GeneDB