Schistosomiasis affects approximately 210 million people in 76 countries, is a cause of serious morbidity and is estimated to account for greater than a quarter of a million deaths per annum. Schistosomiasis is caused by blood flukes of the genus Schistosoma (phylum Platyhelminthes) and S. mansoni is one of the three major subspecies. Further information can be found on the World Health Organization web site.
The S. mansoni genome is 363Mb in size, G+C content is approximately 35% and encodes at least 11,809 genes. The Pathogen Genomics group at the Wellcome Trust Sanger Institute played a major role in sequencing the draft genome of S. mansoni (see Berriman et al.). The original draft has now been significantly improved and a new version (v5.0) of the S. mansoni genome is now available.
The S. mansoni genome database contains the published v4.0 of the genome. Both the v4.0 and v3.1 gene predictions can be viewed as separate tracks of annotation in Gbrowse (old GeneDB version). A new database build using the latest version 5.0 data is now available.
» Schistosoma mansoni on GeneDB
New version of the genome
Example Gene in latest v5.0 annotation (visualised in webartemis)
Viewing RNAseq alignments against the V5 assembly in Web-Artemis
» Open Web-Artemis
» From View, you can select RNAseq alignments
Organism specific BLAST
Citing these data