Entamoeba histolytica GeneDB

Entamoeba histolytica is the causal agent of amoebic dysentery and amoebic liver abscess. With an estimated 40 million cases worldwide and 100,000 deaths, it is responsible for agreat deal of suffering, particularly in the developing world.

The Wellcome Trust Sanger Institute Pathogen Sequencing Unit, in collaboration with Graham Clark at the London School of Hygiene and Tropical Medicine, has undertaken whole genome shotgun sequencing of E. histolytica. The E. histolytica genome is believed to be around 18-20 Mb in size and split into 14 chromosomes. This genome sequencing will be carried out in collaboration with The Institute of Genome Research, with each Institute doing half of the sequencing.

This sequencing centre plans on publishing the completed and annotated sequences in a peer-reviewed journal as soon as possible. Permission of the principal investigator should be obtained before publishing analyses of the sequence/open reading frames/genes on a chromosome or genome scale.

Please address all sequencing enquiries to Dr. Matt Berriman (Project Manager - email: mb4@sanger.ac.uk).

19th Sep 2004
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