Leishmania braziliensis GeneDB

The genome of L. braziliensis is the third Leishmania spp to be sequenced at the Sanger Institute. The clone used was generated a whole genome shotgun sequence to ~5x coverage of L. braziliensis clone M2904 (MHOM/BR/75M2904). This pathogen is the causitive agent of cutaneous and the destructive mucocutaneous leishmaniasis in South America. This project is a collaboration with Angela Cruz (Universidade de Sao Paulo -FMRP - USP) and Professor Debbie Smith (Imperial College). Gene prediction and annotation has been partly generated and analysed by comparison to the L. major genome. As sequencing and annotation are in progress, the data is continually updated.

Version 2 of the Leishmania braziliensis is now available. The dataset is a preliminary attempt at ordering and annotating the shotgun data. Assembled contigs have been artificially ordered into pseudomolecules representing the 35 chromosomes based on conservation with Leishmania major. Sequence gaps exist within these assembled contigs. Users should be aware of the preliminary nature of the assembly which will improve as finishing continues. Annotation has been transfered to the predicted genes from the orthologs in Leishmania major.

8312 genes in GeneDB
20 January 2007
28 March 2008
Orthologue links between the Leishmania species updated
15 February 2008
Leishmania mexicana shotgun reads are now available to download from our ftp site and for searching from the L. major blast server.
27 November 2006
Version 2.0 of Leishmania braziliensis now available in GeneDB