Salmonella typhi GeneDB

The sequenced strain, CT18, is a highly pathogenic, multiple drug resistant strain isolated from a typhoid patient in Cho Quan Hospital, Ho Chi Minh City, Vietnam. The chromosome sequence is 4,809,037 bp in length with a G+C content of 52.09%, and was generated from 97,000 shotgun reads. The start of the sequence was chosen to correspond with the start of the published E. coli K12 sequence. There are 4,599 protein-coding genes (including 204 pseudogenes). Both the sequence and annotation have been deposited in the public databases with the accession number AL513382. In addition, there are two plasmids: pHCM1 (218,150 bp, 249 CDS) with the accession number AL513383, and pHCM2 (106,516 bp, 131 CDS) with the accession number AL513384.

The sequence and annotation was produced in collaboration with Gordon Dougan of the Department of Biochemistry, Imperial College, London.

Reference:

"Complete genome sequence of a multiple drug resistant Salmonella enterica serovar Typhi CT18" Nature 413 848-852.

J. Parkhill, G. Dougan, K.D. James, N.R. Thomson, D. Pickard, J. Wain, C. Churcher, K. Mungall, S.D. Bentley, M.T.G. Holden, M. Sebaihia, S. Baker, D. Basham, K. Brooks, T. Chillingworth, P. Connerton, A. Cronin, P. Davis, R.M. Davies, L. Dowd, N. White, J. Farrar, T. Feltwell, N. Hamlin, A. Haque, T.T. Hien, S. Holroyd, K. Jagels, A. Krogh, T.S. Larsen, S. Leather, S. Moule, P. O'Gaora, C. Parry, M. Quail, K. Rutherford, M. Simmonds, J. Skelton, K. Stevens, S. Whitehead, and B.G. Barrell

Please address all enquiries to Julian Parkhill (parkhill@sanger.ac.uk).