Trypanosoma congolense GeneDB

The Wellcome Trust Sanger Institute Pathogen Sequencing Unit (PSU) is partially shotgun sequencing the nuclear genome of the livestock-infective Trypanosoma congolense. This will serve as a useful comparative genomics resource to complement the genomes of Trypanosoma vivax and Trypanosoma brucei and Trypanosoma brucei gambiense. The T. congolense and T. vivax partial shotgun projects are being carried out in collaboration with David Barry (Glasgow University, UK), Alberto Davila (Instituto Oswalso Cruz, Brazil), Phelix Majiwa and Sara Melville (University of Cambridge, UK). The current assembly consists of a ca. 5x whole genome shotgun which was further assembled/analysed by comparison to the T. brucei genome. Contigs from the T. congolense assembly were ordered using regions of conserved synteny with T. brucei chromosomes and, based on this, are represented here as 11 pseudomolecules. Product assignments were transferred between putative orthologues. Gene models are coloured according to their level of similarity to T. brucei coding sequences, where presumed orthologues are have been assigned a dark purple colour, models with similarity to T. brucei genes are represented in pale purple and T. congolense sequences without any apparent similarity to T. brucei genes are coloured pale blue.

We are aware of 3000 contaminating reads from the mouse genome and are in the process of removing these as well as reassembling the data (May 2005).

Please address all sequencing enquiries to Dr. Matt Berriman (Project Manager - email: mb4@sanger.ac.uk).
Please note that the data are very preliminary.

6th Mar 2006
Protein families and domains updated
(InterPro release 12.0)

2nd Feb 2005
Release of the first T. congolense assembly